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Piloting on-site interventions for reducing antimicrobial use in livestock farming in emerging economies

Increasing intensification and expansion of the livestock sector in emerging economies is a large user of antimicrobials, driving the global emergence of antimicrobial resistant bacteria in livestock, humans and the environment. The objective of this project is to test interventions aimed to reduce antimicrobial use (AMU) in livestock in emerging economies using the pig production in Thailand as a study case.

Regulations may not be sufficient to reduce AMU in the livestock sector and can therefore have limited impact on the resulting development of AMR in the biota. Thus, there is a need to find interventions that do not depend solely on regulation. The novelty of the project is that it will test interventions by computer simulations based on primary data generated through a One Health approach.

Research approach

Based on known distributions of pig production the research team will record knowledge, attitudes and practices related to AMU and animal management among pig farmers. Then they will collect samples from pigs, pig farmers and control human subjects who are not in contact with pigs and perform phenotypic and molecular analysis of the AMR profiles.

Using these data-sets, the researchers will perform spatial analyses and model the impacts of altering variables for practices related to AMU, animal management and farm structure, with emphasis on farmers’ incentives, to explore whether these would be expected to lead to a reduction in AMU. It will be assessed if such a reduction can be related to the burden of AMR in pigs, pig farmers and non-exposed humans. Finally, the economic and social feasibility of the tested interventions will be evaluated.

The project was recently funded by a JPIAMR grant in the 2017 call for transnational research projects “Comparison of prevention, control and intervention strategies for AMR infections through multidisciplinary studies, including One Health approaches”. 

Partners in the consortium are Ulf Magnusson, SLU, Josef Järhult, UU, Thomas P. van Beckel, ETH Zürich, and Marianne Sunde, Norwegian Veterinary Institute.

More information:
Web news about the project
Ulf Magnusson’s research
Josef Järhult’s research
JPIAMR